LN Ultra: Cryo Attachment for PowerTome

LN Ultra: Cryo Attachment for PowerTome

Cryo ultramicrotomy sectioning of both biological and industrial materials can be achieved with the LN Ultra, a liquid nitrogen-cooled cryo-chamber attachment for the PowerTome series of ultramicrotomes.

Manufacturer

RMC Boeckeler

Boeckeler Instruments engineers sample preparation equipment for nanoscale research, under the RMC Boeckeler product line. Their solutions are employed in both life sciences and materials research, with special emphasis in sample preparation for 3D electron microscopy.

Key Features

  • Provides optimal thermal stability necessary for producing cryosections
  • Capable of holding temperatures from +40°C to -185°C
  • Stable environment is perfect for sectioning and planning a variety of samples
  • Capable of providing a stable sectioning environment for up to nine hours

Overview

Rapid freezing and Freeze Substitution are one method of making cellular structure and organisation appear closer to the natural state but this process can limit other avenues of investigation, such as immunohistochemical applications.

Dehydration of a sample, necessary for routine electron microscopy of biological tissue, can be a major source of artefact and in many cases inhibits antibody-antigen reactions essential for immunolabelling/gold labelling studies. If a method could be found to preserve the water content in the cell during the process, this would greatly increase the scope of investigations, and the work Professor K.T. Tokuyasu provided for this breakthrough.

Today, cryosectioning and labelling of tissues and cell cultures by the ‘Tokuyasu Technique’ is a routine application in many laboratories.

Cryo ultramicrotomy sectioning of both biological and industrial materials can be achieved with the LN Ultra, a liquid nitrogen-cooled cryo-chamber attachment for the PowerTome series of ultramicrotomes. Mounted onto the PowerTome, the LN Ultra provides optimal thermal stability necessary for producing cryosections.

Capable of holding temperatures from +40°C to -185°C, the stable environment of the LN Ultra is perfect for sectioning and planning a variety of samples. These may include rubber and soft polymers, or biological cells and tissues; used for example, for immunolabelling using the Tokuyasu technique or CEMOVIS (Cryo-Electron Microscopy of Vitreous Ice Sections).

Liquid Nitrogen consumption is very low, allowing for a size efficient 15.5-litre dewar, capable of providing a stable sectioning environment for up to nine hours, depending on your technique and application, thus saving your laboratory LN2 costs over less efficient systems.

Downloads

Technical Specifications

LN Ultra Datasheet

View Technical Specification

Service Support

Comprehensive repairs and servicing

Annual Support Programs

Your metrology instrumentation is a major investment that is critical to your business operation and success. In today’s competitive climate, it is more important than ever to extend the functionality and peak performance of your metrology equipment years beyond the expiration of your factory warranty. CN Tech’s Support Programs will help ensure that your investment is protected, and that you and your instrument’s are always operating at peak performance.

With over 20 years’ experience servicing and repairing you can be assured that your system is in safe hands. The independent services we offer include system relocation, maintenance visits, parts and consumables, and break down interventions.

CN Tech’s Support Programs are an economical way to guarantee optimal working condition:

  • Annual Preventive Maintenance
  • Priority Technical Assistance
  • Preferred Parts Availability
  • On-Site User Training
  • Remote Diagnostics
  • No surprise repair expense and much more!

Support Contact Example

An example of our service and support contracts are shown below:

Brochures

Metrology & Instrumentation Annual Support Programs 2022/23

CN Tech's Support Programs will help ensure that your investment is protected, and that you and your instrument’s are always operating at peak performance.

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